
Purpose-built biotics

Unlocked Medical Foods

Unlocked Labs develops medical foods that specifically target compounds known to drive chronic health conditions.


Made from safe probiotics

Remove toxins
Unlocked medical foods are powered by our active postbiotic ingredients (APIs): enzyme-rich bacterial husks that actively remove the compounds driving those chronic conditions.
These proprietary, patent-pending ingredients are made from safe probiotic bacteria that we optimized to produce large amounts of active enzymes.
We selected these specific enzymes because of their ability to break down disease-causing toxins in the GI tract, thus directly addressing the root causes of serious health conditions.
Active postbiotic ingredients
The Unlocked Approach

1
Target selection
Unlocked focuses on chronic medical conditions driven by defined compounds that can be targeted within the GI tract
Proven Science
We use well-established and safe microbial enzymes that target specific toxins through scientifically proven mechanisms, and confirm efficiency through rigorous validation.
2
Regulatory efficiency
The unique Medical food + GRAS regulatory pathway combination enables fast, capital-efficient product development while maintaining the highest safety standards.
3
Accessibility
Unlocked Medical foods are not drugs and you don't need a prescription to access them.
4
Product stability
The key ingredients in Unlocked medical foods are enzyme-rich, shelf-stable postbiotics that don't need refrigeration.
5
Safety
Unlocked’s active postbiotic ingredients stay in the GI tract, making them safe compared to other products that enter the circulation and reach throughout the body.
6
StoneShield, powered by OX164
Unlocked’s lead medical food is StoneShield - intended for the dietary management of kidney stone risk.
The active ingredient in StoneShield is OX164, a unique enzyme-rich postbiotic designed to actively break down oxalate - the #1 kidney stone-causing compound.
OX164 breaks down dietary oxalate in the stomach, before the body has a chance to absorb it.

StoneShield is powered by OX164, and formulated with cranberry extract, magnesium citrate, and vitamin B to provide further support for urinary tract health.
StoneShield is designed to be taken with meals to reduce dietary oxalate exposure.
As a medical food, StoneShield is intended for use under physician supervision.
Frequently asked questions

The Unlocked Team
Unlocked Labs is built on deep expertise in microbiology, molecular biology, and metabolic engineering, with a focus on translating enzyme science into effective medical foods products.
In 2020, we identified a gap between the scientific understanding of disease-driving metabolic compounds and the lack of precision in existing probiotic and supplement products.
Unlocked was formed to bridge that gap by developing a platform combining advanced microbial enzyme science, food-grade manufacturing, and efficient regulatory pathways to create targeted medical foods that are safe, scalable, and clinically relevant.
Unlocked's Advisors
The Unlocked team is advised by experts in microbiology, nephrology, and metabolic disease, including clinicians and researchers with experience translating biological insights into active ingredients for effective medical foods.
We are lucky to have industry veterans with backgrounds in manufacturing, FDA regulated product development, and strategic growth planning help us build the company.

John Endres
John works with Unlocked on regulatory filings and dossiers using his 20 years of regulator experience and perfect track record in FDA notifications.

Prof. Pierzynowski
As an emeritus professor with deep experience in developing animal models, Stefan helps Unlocked design and execute preclinical studies.

Amy Clewell
Aided by a passion for natural medicine and a deep knowledge of natural products regulations, Amy helps Unlocked achieve regulatory goals.
Funding Partners
Unlocked is fortunate to have received funding from sources spanning federal research grant agencies, internationally active VC's, state agencies, and angels.
They believed in us when the Unlocked approach was a concept, and helped us grow an idea into a product. They stuck with us and believed in us when the road was rocky and our future unclear.
Research Partners
Unlocked collaborates with research institutions to gain access to unique equipment and facilities that aren't available in-house for pre-clinical studies, micro CT-scanners, etc.
Contact us
If you have any questions, suggestions, comments, or just want to say Hi - don't hesitate to reach out!
1482 Commerce Drive, Unit U
Laramie, WY 82070

















