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Purpose-built biotics

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Unlocked Medical Foods

Unlocked Labs develops medical foods that specifically target compounds known to drive chronic health conditions.

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Made from safe probiotics

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Remove toxins

Unlocked medical foods are powered by our active postbiotic ingredients (APIs): enzyme-rich bacterial husks that actively remove the compounds driving those chronic conditions. ​

​These proprietary, patent-pending ingredients are made from safe probiotic bacteria that we optimized to produce large amounts of active enzymes.

We selected these specific enzymes because of their ability to break down disease-causing toxins in the GI tract, thus directly addressing the root causes of serious health conditions.

Active postbiotic ingredients

The Unlocked Approach

1

Target selection

Unlocked focuses on chronic medical conditions driven by defined compounds that can be targeted within the GI tract

Proven Science

We use well-established and safe microbial enzymes that target specific toxins through scientifically proven mechanisms, and confirm efficiency through rigorous validation.

2

Regulatory efficiency

The unique Medical food + GRAS regulatory pathway combination enables fast, capital-efficient product development while maintaining the highest safety standards.

3

Accessibility

 Unlocked Medical foods are not drugs and you don't need a prescription to access them.

4

Product stability

The key ingredients in Unlocked medical foods are enzyme-rich, shelf-stable postbiotics that don't need refrigeration.

5

Safety

Unlocked’s active postbiotic ingredients stay in the GI tract, making them safe compared to other products that enter the circulation and reach throughout the body.

6

StoneShield, powered by OX164

Unlocked’s lead medical food is StoneShield - intended for the dietary management of kidney stone risk.

The active ingredient in StoneShield is OX164, a unique enzyme-rich postbiotic designed to actively break down oxalate - the #1 kidney stone-causing compound.

OX164 breaks down dietary oxalate in the stomach, before the body has a chance to absorb it.

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StoneShield ​is powered by OX164, and formulated with cranberry extract, magnesium citrate, and vitamin B to provide further support for urinary tract health.

StoneShield is designed to be taken with meals to reduce dietary oxalate exposure.

 

As a medical food, StoneShield is intended for use under physician supervision.

Frequently asked questions

The Unlocked Team

Unlocked Labs is built on deep expertise in microbiology, molecular biology, and metabolic engineering, with a focus on translating enzyme science into effective medical foods products.

In 2020, we identified a gap between the scientific understanding of disease-driving metabolic compounds and the lack of precision in existing probiotic and supplement products.

Unlocked was formed to bridge that gap by developing a platform combining advanced microbial enzyme science, food-grade manufacturing, and efficient regulatory pathways to create targeted medical foods that are safe, scalable, and clinically relevant.

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CEO & Founder

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Christoph Geisler

Christoph is a molecular biology trained founder focused on translating microbial R&D into effective, scalable products. He loves to build impactful solutions to real-world problems.

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Head of Research 

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Michal Luczak

Michal's directs the R&D in the Unlocked lab. With a background in Toxicology from Brown University, his goal is make a difference through affordable healthcare.

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Research Scientist

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Prerana Balasubramanian

Prerana applies her background in fermentation and food technology from UMass to scaling and improving Unlocked's active postbiotic ingredients.

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Head of Marketing

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Christina Segal

Christina's experience in pharmaceutical, biotech and life science companies helps Unlocked's strategic planning, as well as marketing and product development.

Unlocked's Advisors

The Unlocked team is advised by experts in microbiology, nephrology, and metabolic disease, including clinicians and researchers with experience translating biological insights into active ingredients for effective medical foods. 

We are lucky to have industry veterans with backgrounds in manufacturing, FDA regulated product development, and strategic growth planning help us build the company.

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Michael Bush

Growthways consulting

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Ex-Ganeden CEO: experience in (pro)biotic and functional ingredient space, advises on commercialization, strategy, fundraising, 3PL.

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John works with Unlocked on regulatory filings and dossiers using his 20 years of regulator experience and perfect track record in FDA notifications. 

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Prof. Pierzynowski

Lund University, Sweden

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As an emeritus professor with deep experience in developing animal models, Stefan helps Unlocked design and execute preclinical studies.

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David Keller

Keller consulting

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David advises on science related activities, IP, regulatory, DD and clinical trials, with a focus on foods, including ingredients and finished products.

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Aided by a passion for natural medicine and a deep knowledge of natural products regulations, Amy helps Unlocked achieve regulatory goals.

Funding Partners

Unlocked is fortunate to have received funding from sources spanning federal research grant agencies, internationally active VC's, state agencies, and angels.

 

They believed in us when the Unlocked approach was a concept, and helped us grow an idea into a product. They stuck with us and believed in us when the road was rocky and our future unclear.​

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Research Partners

Unlocked collaborates with research institutions to gain access to unique equipment and facilities that aren't available in-house for pre-clinical studies, micro CT-scanners, etc.

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Contact us

If you have any questions, suggestions, comments, or just want to say Hi - don't hesitate to reach out!

1482 Commerce Drive, Unit U

Laramie, WY 82070

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